This image is a huge leap past anything I've seen before, the amount of detail is far beyond what other people have managed to get from the ground (albeit they were using far smaller telescopes), usually most photographs show a T-shaped object fly through the field of view, but the amount of detail in this is incredible.
This is a photograph of the Space Shuttle Atlantis and the International Space Station together, taken from the ground. Atlantis is the lower-left of the image, it is facing away from the telescope and so you can see the engine nozzles, it casts a shadow over the rest of the station. The solar panels to the right of the station are what have just been installed. You can clearly see one of the stations two robotic arms and can easily identify all the separate modules of the station.
Things in orbit are difficult to photograph, as they can pass overhead in just a couple of minutes so getting the telescope to follow them is a difficult challenge.
This is one of the most impressive images I've seen on APOD in a sometime.